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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA AP000866.1 CTRPv2 pan-cancer AAC -0.1 0.003
mRNA PAN2 CTRPv2 pan-cancer AAC -0.11 0.003
mRNA RAB11B GDSC1000 pan-cancer AAC 0.097 0.003
mRNA NIPSNAP3A CTRPv2 pan-cancer AAC 0.1 0.003
mRNA SYNE1 CTRPv2 pan-cancer AAC -0.1 0.003
mRNA GNG8 GDSC1000 pan-cancer AAC 0.098 0.003
mRNA KDELR3 GDSC1000 pan-cancer AAC -0.13 0.003
mRNA NANP CTRPv2 pan-cancer AAC 0.1 0.003
mRNA GLB1 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA GTF3C3 CTRPv2 pan-cancer AAC 0.1 0.003
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