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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA THEMIS2 CTRPv2 pan-cancer AAC 0.11 0.003
mRNA CRTAM CTRPv2 pan-cancer AAC 0.1 0.003
mRNA ELOVL7 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA GAS7 GDSC1000 pan-cancer AAC -0.13 0.003
mRNA IL10RB GDSC1000 pan-cancer AAC -0.11 0.003
mRNA TNFRSF8 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA HEATR6 CTRPv2 pan-cancer AAC 0.1 0.003
mRNA SELPLG CTRPv2 pan-cancer AAC 0.11 0.003
mRNA TNKS GDSC1000 pan-cancer AAC -0.11 0.003
mRNA GDNF GDSC1000 pan-cancer AAC -0.096 0.003
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