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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA NPIPB7 CTRPv2 pan-cancer AAC -0.1 0.003
mRNA CITED2 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA TRABD GDSC1000 pan-cancer AAC -0.11 0.003
mRNA RHPN1 CTRPv2 pan-cancer AAC -0.11 0.003
mRNA SH2D1B CTRPv2 pan-cancer AAC 0.099 0.003
mRNA MAP4K1 CTRPv2 pan-cancer AAC -0.14 0.003
mRNA EPHA10 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA SMPD3 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA SRBD1 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA PPFIBP2 GDSC1000 pan-cancer AAC -0.1 0.003
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