1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA UBE2J1 GDSC1000 pan-cancer AAC -0.12 0.003
mRNA PSMB9 CTRPv2 pan-cancer AAC 0.11 0.003
mRNA TIMP1 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA SIPA1 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA CASP3 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA GOLGA6L4 CTRPv2 pan-cancer AAC 0.1 0.003
mRNA TCF7 CTRPv2 pan-cancer AAC -0.1 0.003
mRNA STAG3 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA GALNT14 GDSC1000 pan-cancer AAC -0.11 0.003
mRNA EPHB1 CTRPv2 pan-cancer AAC 0.1 0.003
Download CSV