1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA EIF3A CTRPv2 pan-cancer AAC 0.11 0.002
mRNA C1orf122 GDSC1000 pan-cancer AAC 0.11 0.002
mRNA MAGI1 CTRPv2 pan-cancer AAC 0.1 0.002
mRNA SKAP1 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA MBOAT7 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA LNPEP CTRPv2 pan-cancer AAC -0.11 0.002
mRNA NUB1 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA TRIM15 GDSC1000 pan-cancer AAC 0.12 0.002
mRNA MME GDSC1000 pan-cancer AAC -0.1 0.002
mRNA EVI2B CTRPv2 pan-cancer AAC -0.12 0.002
Download CSV