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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGAP15 CTRPv2 pan-cancer AAC 0.29 2e-10
mRNA CD2 GDSC1000 pan-cancer AAC 0.21 2e-10
mRNA FAM117A CTRPv2 pan-cancer AAC 0.25 2e-10
mRNA RP11-345F18.1 CTRPv2 pan-cancer AAC 0.21 2e-10
mRNA IGF1 GDSC1000 pan-cancer AAC 0.22 2e-10
mRNA GPR85 GDSC1000 pan-cancer AAC 0.21 2e-10
mRNA CD79B GDSC1000 pan-cancer AAC -0.25 3e-10
mRNA ESYT1 CTRPv2 pan-cancer AAC 0.22 3e-10
mRNA YIF1B CTRPv2 pan-cancer AAC 0.22 3e-10
mRNA LEPR CTRPv2 pan-cancer AAC 0.21 3e-10
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