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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA RHCE CTRPv2 pan-cancer AAC 0.23 4e-12
mRNA SYCP2L CTRPv2 pan-cancer AAC 0.24 4e-12
mRNA CTD-2587H24.4 CTRPv2 pan-cancer AAC 0.24 5e-12
mRNA HK1 CTRPv2 pan-cancer AAC 0.24 5e-12
mRNA PPP1R14A CTRPv2 pan-cancer AAC 0.23 5e-12
mRNA FAM89A CTRPv2 pan-cancer AAC 0.25 6e-12
mRNA RHAG GDSC1000 pan-cancer AAC 0.22 6e-12
mRNA ITGAM CTRPv2 pan-cancer AAC 0.24 7e-12
mRNA MS4A1 GDSC1000 pan-cancer AAC -0.25 7e-12
mRNA PIK3R6 CTRPv2 pan-cancer AAC 0.24 7e-12
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