1. Home/
  2. Compounds/
  3. ruxolitinib

ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA PARP15 GDSC1000 pan-cancer AAC -0.11 0.004
mRNA EMP3 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA MRPS5 GDSC1000 pan-cancer AAC -0.097 0.004
mRNA DNAJC7 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA TMED1 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA SPANXN5 GDSC1000 pan-cancer AAC -0.095 0.004
mRNA ZNF831 CTRPv2 pan-cancer AAC -0.099 0.004
mRNA TUBA1C GDSC1000 pan-cancer AAC 0.12 0.004
mRNA WNT3 CTRPv2 pan-cancer AAC 0.098 0.004
mRNA MSN CTRPv2 pan-cancer AAC 0.11 0.004
Download CSV