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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA ZFPM1 CTRPv2 pan-cancer AAC 0.25 1e-13
mRNA SAMSN1 CTRPv2 pan-cancer AAC 0.27 1e-13
mRNA LRRC7 CTRPv2 pan-cancer AAC 0.25 1e-13
mRNA FAM46C GDSC1000 pan-cancer AAC 0.27 2e-13
mRNA GYPA GDSC1000 pan-cancer AAC 0.23 7e-13
mRNA SMIM1 CTRPv2 pan-cancer AAC 0.24 9e-13
mRNA KEL CTRPv2 pan-cancer AAC 0.24 1e-12
mRNA OTOF CTRPv2 pan-cancer AAC 0.24 1e-12
mRNA CD22 GDSC1000 pan-cancer AAC -0.26 1e-12
mRNA C10orf128 GDSC1000 pan-cancer AAC 0.25 1e-12
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