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ruxolitinib

Synonyms

SourcesNames Used
GDSC1000Ruxolitinib
CTRPv2ruxolitinib
PharmacoGx ruxolitinib

External IDs

DatabaseIdentifier
Smiles: N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12
Pubchem: 25126798

Annotated Targets

JAK2, JAK1, JAK3, TYK2

FDA Approval Status

Approved
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Top molecular features associated with response to ruxolitinib


Feature TypeStandardized
Nominal ANOVA
mRNA FCER1A GDSC1000 pan-cancer AAC 0.26 3e-15
mRNA PRKCQ CTRPv2 pan-cancer AAC 0.28 3e-15
mRNA DNAJC6 CTRPv2 pan-cancer AAC 0.26 6e-15
mRNA CCDC173 GDSC1000 pan-cancer AAC 0.25 7e-15
mRNA GATA2 CTRPv2 pan-cancer AAC 0.28 7e-15
mRNA ATP7B CTRPv2 pan-cancer AAC 0.26 1e-14
mRNA HDC CTRPv2 pan-cancer AAC 0.26 1e-14
mRNA PSMG1 CTRPv2 pan-cancer AAC 0.27 2e-14
mRNA RYR3 CTRPv2 pan-cancer AAC 0.26 3e-14
mRNA TSPAN32 CTRPv2 pan-cancer AAC 0.27 3e-14
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