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SGX-523

SGX-523

Synonyms

Sources	Names Used
CTRPv2	SGX-523
PharmacoGx	SGX-523

External IDs

Database	Identifier
Smiles:	Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1
Pubchem:	24779724

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SGX-523

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	REPS2	CTRPv2	pan-cancer	AAC	0.23	3e-10
mRNA	SMURF1	CTRPv2	pan-cancer	AAC	0.23	3e-10
mRNA	RASEF	CTRPv2	pan-cancer	AAC	0.24	2e-09
mRNA	C20orf202	CTRPv2	pan-cancer	AAC	0.22	1e-08
mRNA	IDS	CTRPv2	pan-cancer	AAC	0.22	2e-08
mRNA	AF011889.5	CTRPv2	pan-cancer	AAC	0.21	2e-08
mRNA	SPINT4	CTRPv2	pan-cancer	AAC	0.2	5e-08
mRNA	NME5	CTRPv2	pan-cancer	AAC	0.21	6e-08
mRNA	TRIM24	CTRPv2	pan-cancer	AAC	0.21	1e-07
mRNA	STEAP1	CTRPv2	pan-cancer	AAC	0.21	1e-07

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