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SGX-523

SGX-523

Synonyms

Sources	Names Used
CTRPv2	SGX-523
PharmacoGx	SGX-523

External IDs

Database	Identifier
Smiles:	Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1
Pubchem:	24779724

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SGX-523

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	COPS6	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	PNPLA8	CTRPv2	pan-cancer	AAC	0.16	1e-05
mRNA	RFFL	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	ABO	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	NAALADL2	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	GNB2	CTRPv2	pan-cancer	AAC	0.16	1e-05
mRNA	POLR2J2	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	DUS4L	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	WDR35	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	OR4C6	CTRPv2	pan-cancer	AAC	0.15	2e-05

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