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SGX-523

SGX-523

Synonyms

Sources	Names Used
CTRPv2	SGX-523
PharmacoGx	SGX-523

External IDs

Database	Identifier
Smiles:	Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1
Pubchem:	24779724

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SGX-523

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SH3RF1	CTRPv2	pan-cancer	AAC	0.19	3e-06
mRNA	LSM8	CTRPv2	pan-cancer	AAC	0.18	3e-06
mRNA	LYZ	CTRPv2	pan-cancer	AAC	0.17	3e-06
mRNA	C9orf43	CTRPv2	pan-cancer	AAC	0.17	3e-06
mRNA	PPM1G	CTRPv2	pan-cancer	AAC	0.17	4e-06
mRNA	BAIAP2L1	CTRPv2	pan-cancer	AAC	0.2	4e-06
mRNA	FAM160A1	CTRPv2	pan-cancer	AAC	0.19	4e-06
mRNA	OPTC	CTRPv2	pan-cancer	AAC	0.17	5e-06
mRNA	BPIFB1	CTRPv2	pan-cancer	AAC	0.16	7e-06
mRNA	EPHB4	CTRPv2	pan-cancer	AAC	0.18	7e-06

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