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SGX-523

SGX-523

Synonyms

Sources	Names Used
CTRPv2	SGX-523
PharmacoGx	SGX-523

External IDs

Database	Identifier
Smiles:	Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1
Pubchem:	24779724

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SGX-523

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TMEM121	CTRPv2	pan-cancer	AAC	-0.064	0.09
mRNA	SCGB1D1	CTRPv2	pan-cancer	AAC	-0.061	0.09
mRNA	ATP10A	CTRPv2	pan-cancer	AAC	0.065	0.09
mRNA	SCT	CTRPv2	pan-cancer	AAC	-0.062	0.09
mRNA	GPR171	CTRPv2	pan-cancer	AAC	0.061	0.09
mRNA	CMKLR1	CTRPv2	pan-cancer	AAC	0.061	0.09
mRNA	CCDC102B	CTRPv2	pan-cancer	AAC	0.064	0.09
mRNA	ZBTB18	CTRPv2	pan-cancer	AAC	-0.065	0.09
mRNA	UQCRQ	CTRPv2	pan-cancer	AAC	-0.065	0.09
mRNA	RPL15	CTRPv2	pan-cancer	AAC	-0.07	0.09

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