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SGX-523

SGX-523

Synonyms

Sources	Names Used
CTRPv2	SGX-523
PharmacoGx	SGX-523

External IDs

Database	Identifier
Smiles:	Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1
Pubchem:	24779724

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SGX-523

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DNMBP	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	MEPCE	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	SGCB	CTRPv2	pan-cancer	AAC	0.17	0.0002
mRNA	STEAP2	CTRPv2	pan-cancer	AAC	0.16	0.0002
mRNA	FAP	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	SPAG9	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	RP11-697E2.12	CTRPv2	pan-cancer	AAC	-0.16	0.0002
mRNA	SOCS6	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	RP11-697E2.6	CTRPv2	pan-cancer	AAC	-0.15	0.0002
mRNA	ANKIB1	CTRPv2	pan-cancer	AAC	0.13	0.0003

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