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OSI-930

OSI-930

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	OSI-930
PharmacoGx	OSI-930

External IDs

Database	Identifier
Smiles:	FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Pubchem:	9868037

Annotated Targets

KIT, KDR, FLT1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-930

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MDN1	CTRPv2	pan-cancer	AAC	0.19	9e-07
mRNA	INPP5D	GDSC1000	pan-cancer	AAC	0.26	9e-07
mRNA	PHF14	CTRPv2	pan-cancer	AAC	0.18	9e-07
mRNA	RBMX	CTRPv2	pan-cancer	AAC	0.19	1e-06
mRNA	ZMYM3	CTRPv2	pan-cancer	AAC	0.19	1e-06
mRNA	FAM78A	CTRPv2	pan-cancer	AAC	0.22	1e-06
mRNA	WRN	CTRPv2	pan-cancer	AAC	0.19	1e-06
mRNA	BEND3	CTRPv2	pan-cancer	AAC	0.19	1e-06
mRNA	CCR2	GDSC1000	pan-cancer	AAC	0.17	1e-06
mRNA	FHL3	GDSC1000	pan-cancer	AAC	0.17	1e-06

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