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OSI-930

OSI-930

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	OSI-930
PharmacoGx	OSI-930

External IDs

Database	Identifier
Smiles:	FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Pubchem:	9868037

Annotated Targets

KIT, KDR, FLT1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-930

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GCFC2	CTRPv2	pan-cancer	AAC	0.18	6e-07
mRNA	PRR3	CTRPv2	pan-cancer	AAC	0.21	6e-07
mRNA	ATP8B4	GDSC1000	pan-cancer	AAC	0.18	6e-07
mRNA	MATK	GDSC1000	pan-cancer	AAC	0.17	6e-07
mRNA	TGM5	GDSC1000	pan-cancer	AAC	0.17	7e-07
mRNA	SMARCC1	CTRPv2	pan-cancer	AAC	0.2	7e-07
mRNA	RNF138	CTRPv2	pan-cancer	AAC	0.2	7e-07
mRNA	SF1	CTRPv2	pan-cancer	AAC	0.2	7e-07
mRNA	GP1BB	CTRPv2	pan-cancer	AAC	0.19	7e-07
mRNA	CX3CR1	GDSC1000	pan-cancer	AAC	0.17	7e-07

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