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OSI-930

Synonyms

SourcesNames Used
GDSC1000, CTRPv2OSI-930
PharmacoGx OSI-930

External IDs

DatabaseIdentifier
Smiles: FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Pubchem: 9868037

Annotated Targets

KIT, KDR, FLT1

FDA Approval Status

Not Approved
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Top molecular features associated with response to OSI-930


Feature TypeStandardized
Nominal ANOVA
mRNA OR10H4 GDSC1000 pan-cancer AAC -0.098 0.003
mRNA RPS6KA1 GDSC1000 pan-cancer AAC 0.12 0.003
mRNA KRTAP13-2 GDSC1000 pan-cancer AAC 0.1 0.003
mRNA AQR CTRPv2 pan-cancer AAC 0.11 0.003
mRNA GRK3 CTRPv2 pan-cancer AAC 0.12 0.003
mRNA CENPN GDSC1000 pan-cancer AAC -0.098 0.003
mRNA TADA1 CTRPv2 pan-cancer AAC 0.12 0.003
mRNA AP5B1 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA GRIA2 CTRPv2 pan-cancer AAC 0.11 0.003
mRNA CYP2C18 CTRPv2 pan-cancer AAC 0.11 0.003
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