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OSI-930

OSI-930

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	OSI-930
PharmacoGx	OSI-930

External IDs

Database	Identifier
Smiles:	FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Pubchem:	9868037

Annotated Targets

KIT, KDR, FLT1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-930

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CDR2	GDSC1000	pan-cancer	AAC	-0.11	0.003
mRNA	DDX51	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	HIGD1B	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	ACRV1	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	LHX2	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	KLF16	GDSC1000	pan-cancer	AAC	0.1	0.003
mRNA	ZNF407	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	MCRS1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	GFPT1	GDSC1000	pan-cancer	AAC	-0.11	0.003
mRNA	HACD4	GDSC1000	pan-cancer	AAC	0.11	0.003

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