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regorafenib

regorafenib

Synonyms

Sources	Names Used
CTRPv2	regorafenib
PharmacoGx	regorafenib

External IDs

Database	Identifier
Pubchem:	11167602

Annotated Targets

FRK, DDR2, MAPK11, KIT, BRAF, TEK, ABL1, EPHA2, FGFR1, FGFR2, FLT1, FLT4, KDR, NTRK1, PDGFRA, PDGFRB, RAF1, RET

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to regorafenib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SPRY4	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	ISL2	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	PIWIL4	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	IL17RA	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	FARSA	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	DISC1	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	TTC28	CTRPv2	pan-cancer	AAC	0.16	0.0002
mRNA	LEO1	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	SMIM3	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	ATP6V1G2-DDX39B	CTRPv2	pan-cancer	AAC	0.15	0.0002

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