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regorafenib

Synonyms

SourcesNames Used
CTRPv2regorafenib
PharmacoGx regorafenib

External IDs

DatabaseIdentifier
Pubchem: 11167602

Annotated Targets

FRK, DDR2, MAPK11, KIT, BRAF, TEK, ABL1, EPHA2, FGFR1, FGFR2, FLT1, FLT4, KDR, NTRK1, PDGFRA, PDGFRB, RAF1, RET

FDA Approval Status

Approved
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Top molecular features associated with response to regorafenib


Feature TypeStandardized
Nominal ANOVA
mRNA DNAJB2 CTRPv2 pan-cancer AAC -0.14 0.0002
mRNA ZCCHC6 CTRPv2 pan-cancer AAC -0.14 0.0002
mRNA DOT1L CTRPv2 pan-cancer AAC 0.18 0.0002
mRNA HOXD8 CTRPv2 pan-cancer AAC 0.16 0.0002
mRNA ZNF696 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA TCP1 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA CNKSR3 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA LRRC8C CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA C1QC CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA DLX2 CTRPv2 pan-cancer AAC 0.13 0.0003
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