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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA EAF2 CTRPv2 pan-cancer AAC 0.21 9e-06
mRNA ARID2 GDSC1000 pan-cancer AAC 0.15 9e-06
mRNA POLR3G GDSC1000 pan-cancer AAC -0.14 1e-05
mRNA LIPI GDSC1000 pan-cancer AAC 0.17 1e-05
mRNA KDM3B GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA ZNF563 GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA TAL1 CTRPv2 pan-cancer AAC -0.16 1e-05
mRNA P2RY8 CTRPv2 pan-cancer AAC 0.22 1e-05
mRNA ASZ1 CTRPv2 pan-cancer AAC 0.16 1e-05
mRNA GMIP GDSC1000 pan-cancer AAC 0.17 1e-05
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