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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA DNAJC6 CTRPv2 pan-cancer AAC -0.16 2e-05
mRNA NEU3 CTRPv2 pan-cancer AAC -0.16 0.0004
mRNA GYPE CTRPv2 pan-cancer AAC -0.16 2e-05
mRNA GCSAML CTRPv2 pan-cancer AAC -0.16 2e-05
mRNA PPP1R26 CTRPv2 pan-cancer AAC -0.16 0.0001
mRNA FHL2 GDSC1000 pan-cancer AAC -0.16 7e-05
mRNA INPP1 GDSC1000 pan-cancer AAC -0.16 6e-06
mRNA HPCAL1 GDSC1000 pan-cancer AAC -0.16 2e-06
mRNA HHEX CTRPv2 pan-cancer AAC -0.16 8e-05
mRNA POPDC3 GDSC1000 pan-cancer AAC -0.15 6e-06
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