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ZSTK474

ZSTK474

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	ZSTK474
PharmacoGx	ZSTK474

External IDs

Database	Identifier
Smiles:	FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem:	11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ZSTK474

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C9orf64	GDSC1000	pan-cancer	AAC	-0.084	0.008
mRNA	KLHL1	GDSC1000	pan-cancer	AAC	0.083	0.008
mRNA	CTBS	GDSC1000	pan-cancer	AAC	-0.08	0.008
mRNA	ADNP	GDSC1000	pan-cancer	AAC	0.084	0.008
mRNA	BOLL	GDSC1000	pan-cancer	AAC	0.082	0.008
mRNA	SAP30	GDSC1000	pan-cancer	AAC	0.093	0.008
mRNA	DTX4	GDSC1000	pan-cancer	AAC	0.089	0.008
mRNA	CLUL1	GDSC1000	pan-cancer	AAC	0.083	0.008
mRNA	OR5AP2	GDSC1000	pan-cancer	AAC	0.08	0.008
mRNA	MED16	GDSC1000	pan-cancer	AAC	0.082	0.008

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