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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA C1orf101 GDSC1000 pan-cancer AAC 0.12 5e-05
mRNA VPREB1 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA SPIN4 CTRPv2 pan-cancer AAC -0.15 5e-05
mRNA DLG2 GDSC1000 pan-cancer AAC 0.14 5e-05
mRNA LEPR CTRPv2 pan-cancer AAC -0.15 6e-05
mRNA CD79A GDSC1000 pan-cancer AAC 0.15 6e-05
mRNA CD79B CTRPv2 pan-cancer AAC 0.16 6e-05
mRNA CALU GDSC1000 pan-cancer AAC -0.16 6e-05
mRNA FAM49A GDSC1000 pan-cancer AAC 0.13 6e-05
mRNA AIFM2 GDSC1000 pan-cancer AAC -0.13 6e-05
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