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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA KLHDC10 GDSC1000 pan-cancer AAC -0.084 0.008
mRNA RBM5 GDSC1000 pan-cancer AAC 0.095 0.008
mRNA PARVB CTRPv2 pan-cancer AAC -0.11 0.008
mRNA PBRM1 GDSC1000 pan-cancer AAC 0.095 0.008
mRNA PIK3AP1 GDSC1000 pan-cancer AAC 0.11 0.008
mRNA SLA GDSC1000 pan-cancer AAC 0.099 0.008
mRNA ADGRG3 CTRPv2 pan-cancer AAC -0.097 0.008
mRNA VAMP3 GDSC1000 pan-cancer AAC -0.099 0.008
mRNA LGR6 GDSC1000 pan-cancer AAC 0.086 0.008
mRNA ADORA2B GDSC1000 pan-cancer AAC -0.099 0.008
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