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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA TNFRSF9 GDSC1000 pan-cancer AAC -0.083 0.008
mRNA MTHFD2 GDSC1000 pan-cancer AAC -0.092 0.008
mRNA NMT2 GDSC1000 pan-cancer AAC -0.091 0.008
mRNA GGA3 GDSC1000 pan-cancer AAC 0.094 0.008
mRNA FAAP20 CTRPv2 pan-cancer AAC -0.096 0.008
mRNA PPP3CC CTRPv2 pan-cancer AAC 0.11 0.008
mRNA TMEM5 CTRPv2 pan-cancer AAC -0.1 0.008
mRNA LIN7C CTRPv2 pan-cancer AAC -0.1 0.008
mRNA IGSF11 GDSC1000 pan-cancer AAC -0.093 0.008
mRNA FKBPL GDSC1000 pan-cancer AAC 0.083 0.008
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