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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA SYNCRIP GDSC1000 pan-cancer AAC 0.12 6e-05
mRNA GYPB CTRPv2 pan-cancer AAC -0.15 6e-05
mRNA AL445183.1 CTRPv2 pan-cancer AAC 0.14 6e-05
mRNA STIM2 GDSC1000 pan-cancer AAC 0.13 6e-05
mRNA ALDH5A1 CTRPv2 pan-cancer AAC 0.16 6e-05
mRNA CD59 GDSC1000 pan-cancer AAC -0.14 6e-05
mRNA JMJD1C GDSC1000 pan-cancer AAC 0.13 6e-05
mRNA BCL11B GDSC1000 pan-cancer AAC 0.13 7e-05
mRNA TAF6L GDSC1000 pan-cancer AAC 0.12 7e-05
mRNA ST8SIA6 CTRPv2 pan-cancer AAC -0.14 7e-05
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