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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA SET GDSC1000 pan-cancer AAC 0.11 0.0008
mRNA JUN GDSC1000 pan-cancer AAC -0.12 0.0008
mRNA GAB2 CTRPv2 pan-cancer AAC -0.12 0.0008
mRNA ARRB1 CTRPv2 pan-cancer AAC -0.12 0.0008
mRNA SETX GDSC1000 pan-cancer AAC 0.11 0.0008
mRNA PYHIN1 GDSC1000 pan-cancer AAC 0.11 0.0009
mRNA MAN2A2 CTRPv2 pan-cancer AAC -0.13 0.0009
mRNA FAM114A1 GDSC1000 pan-cancer AAC -0.13 0.0009
mRNA PARP1 CTRPv2 pan-cancer AAC 0.14 0.0009
mRNA ARID5B GDSC1000 pan-cancer AAC 0.11 0.0009
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