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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA PDE7A GDSC1000 pan-cancer AAC 0.12 0.0008
mRNA PGPEP1 CTRPv2 pan-cancer AAC -0.13 0.0008
mRNA PDIA5 GDSC1000 pan-cancer AAC -0.1 0.0008
mRNA CD22 GDSC1000 pan-cancer AAC 0.12 0.0008
mRNA PLP2 GDSC1000 pan-cancer AAC -0.11 0.0008
mRNA CEP350 GDSC1000 pan-cancer AAC 0.11 0.0008
mRNA TEC GDSC1000 pan-cancer AAC 0.12 0.0008
mRNA RCN3 GDSC1000 pan-cancer AAC -0.12 0.0008
mRNA SYS1-DBNDD2 CTRPv2 pan-cancer AAC -0.14 0.0008
mRNA BCLAF1 GDSC1000 pan-cancer AAC 0.11 0.0008
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