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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA S100A6 GDSC1000 pan-cancer AAC -0.17 4e-06
mRNA NDST3 GDSC1000 pan-cancer AAC 0.14 4e-06
mRNA NLRC3 GDSC1000 pan-cancer AAC 0.21 4e-06
mRNA MAST3 CTRPv2 pan-cancer AAC 0.19 4e-06
mRNA SMARCE1 GDSC1000 pan-cancer AAC 0.14 4e-06
mRNA CDK13 GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA TOP2B GDSC1000 pan-cancer AAC 0.17 5e-06
mRNA KMO GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA ZNF100 GDSC1000 pan-cancer AAC 0.16 5e-06
mRNA FOXO1 CTRPv2 pan-cancer AAC 0.17 6e-06
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