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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA ANKRD28 GDSC1000 pan-cancer AAC -0.11 0.0007
mRNA ZNF879 GDSC1000 pan-cancer AAC 0.11 0.0007
mRNA ZNF433 GDSC1000 pan-cancer AAC 0.11 0.0007
mRNA THAP9 GDSC1000 pan-cancer AAC 0.11 0.0007
mRNA PPT2-EGFL8 CTRPv2 pan-cancer AAC -0.13 0.0007
mRNA PARP3 GDSC1000 pan-cancer AAC -0.11 0.0007
mRNA OFD1 GDSC1000 pan-cancer AAC 0.11 0.0007
mRNA LILRB1 CTRPv2 pan-cancer AAC 0.13 0.0007
mRNA MTHFS CTRPv2 pan-cancer AAC -0.13 0.0007
mRNA MPEG1 GDSC1000 pan-cancer AAC 0.11 0.0007
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