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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA KIFC3 GDSC1000 pan-cancer AAC -0.13 0.0006
mRNA RASGEF1B GDSC1000 pan-cancer AAC 0.11 0.0006
mRNA RNF122 GDSC1000 pan-cancer AAC 0.11 0.0006
mRNA PTK2B GDSC1000 pan-cancer AAC 0.14 0.0006
mRNA UBE2J1 CTRPv2 pan-cancer AAC 0.14 0.0006
mRNA GSS CTRPv2 pan-cancer AAC -0.13 0.0007
mRNA ADORA2B CTRPv2 pan-cancer AAC -0.14 0.0007
mRNA GLTP GDSC1000 pan-cancer AAC -0.12 0.0007
mRNA BCL2L13 GDSC1000 pan-cancer AAC -0.11 0.0007
mRNA N4BP3 CTRPv2 pan-cancer AAC 0.13 0.0007
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