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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA MDFI GDSC1000 pan-cancer AAC 0.16 2e-06
mRNA NCF1 CTRPv2 pan-cancer AAC 0.19 2e-06
mRNA NFE2 CTRPv2 pan-cancer AAC -0.18 2e-06
mRNA TCF4 CTRPv2 pan-cancer AAC 0.19 2e-06
mRNA SNX22 GDSC1000 pan-cancer AAC 0.16 2e-06
mRNA ZNF627 GDSC1000 pan-cancer AAC 0.15 2e-06
mRNA SMIM14 CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA HPCAL1 GDSC1000 pan-cancer AAC -0.16 2e-06
mRNA PTK2B CTRPv2 pan-cancer AAC 0.22 2e-06
mRNA TNFRSF13C CTRPv2 pan-cancer AAC 0.19 3e-06
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