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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA FURIN GDSC1000 pan-cancer AAC -0.11 0.0003
mRNA ZNRF1 CTRPv2 pan-cancer AAC -0.14 0.0003
mRNA ARID4A GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA NOL8 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA FTL GDSC1000 pan-cancer AAC -0.11 0.0003
mRNA RAPGEF1 CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA C19orf18 GDSC1000 pan-cancer AAC 0.11 0.0003
mRNA ABCA12 CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA CYFIP2 CTRPv2 pan-cancer AAC 0.16 0.0003
mRNA AUTS2 GDSC1000 pan-cancer AAC 0.12 0.0003
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