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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA CR1L CTRPv2 pan-cancer AAC -0.18 6e-07
mRNA RBBP6 GDSC1000 pan-cancer AAC 0.17 7e-07
mRNA UGT3A2 GDSC1000 pan-cancer AAC 0.18 7e-07
mRNA NCKAP1 GDSC1000 pan-cancer AAC -0.29 8e-07
mRNA PRPF4B GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA EPC1 GDSC1000 pan-cancer AAC 0.17 1e-06
mRNA SAMSN1 CTRPv2 pan-cancer AAC -0.19 1e-06
mRNA DOCK8 GDSC1000 pan-cancer AAC 0.22 1e-06
mRNA ANKRD55 CTRPv2 pan-cancer AAC -0.18 2e-06
mRNA GNG12 GDSC1000 pan-cancer AAC -0.22 2e-06
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