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ZSTK474

ZSTK474

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	ZSTK474
PharmacoGx	ZSTK474

External IDs

Database	Identifier
Smiles:	FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem:	11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ZSTK474

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C11orf24	GDSC1000	pan-cancer	AAC	-0.12	0.0001
mRNA	CCL22	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	LILRB5	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	CCDC78	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	ATAD2B	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	LRRC3B	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	PPP1R26	CTRPv2	pan-cancer	AAC	-0.16	0.0001
mRNA	PHF6	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	STK38	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	UBR5	CTRPv2	pan-cancer	AAC	0.15	0.0002

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