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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA SH3GLB1 GDSC1000 pan-cancer AAC -0.12 0.0001
mRNA SDPR CTRPv2 pan-cancer AAC -0.14 0.0001
mRNA IKZF1 GDSC1000 pan-cancer AAC 0.29 0.0001
mRNA IL23R CTRPv2 pan-cancer AAC -0.14 0.0001
mRNA PAX5 CTRPv2 pan-cancer AAC 0.16 0.0001
mRNA TCL1A GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA RP4-583P15.14 CTRPv2 pan-cancer AAC 0.15 0.0001
mRNA CD52 CTRPv2 pan-cancer AAC 0.16 0.0001
mRNA SLC27A2 CTRPv2 pan-cancer AAC -0.15 0.0001
mRNA TAPT1 GDSC1000 pan-cancer AAC 0.13 0.0001
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