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ZSTK474

ZSTK474

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	ZSTK474
PharmacoGx	ZSTK474

External IDs

Database	Identifier
Smiles:	FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem:	11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ZSTK474

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF439	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	AKAP8	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	GRAPL	CTRPv2	pan-cancer	AAC	0.16	0.0001
mRNA	KEL	CTRPv2	pan-cancer	AAC	-0.14	0.0001
mRNA	STXBP5	CTRPv2	pan-cancer	AAC	-0.14	0.0001
mRNA	ARHGDIG	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	CBLN3	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	PSMG1	CTRPv2	pan-cancer	AAC	-0.15	0.0001
mRNA	ZNF92	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	FAM76B	GDSC1000	pan-cancer	AAC	0.13	0.0001

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