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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF117 GDSC1000 pan-cancer AAC 0.12 8e-05
mRNA HHEX CTRPv2 pan-cancer AAC -0.16 8e-05
mRNA CYTH1 CTRPv2 pan-cancer AAC 0.16 8e-05
mRNA VCPKMT CTRPv2 pan-cancer AAC 0.15 8e-05
mRNA RBM39 GDSC1000 pan-cancer AAC 0.12 8e-05
mRNA FAM117A GDSC1000 pan-cancer AAC 0.15 8e-05
mRNA CNRIP1 CTRPv2 pan-cancer AAC -0.15 8e-05
mRNA YTHDC1 GDSC1000 pan-cancer AAC 0.13 8e-05
mRNA KIAA0922 GDSC1000 pan-cancer AAC 0.15 9e-05
mRNA MS4A1 CTRPv2 pan-cancer AAC 0.15 9e-05
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