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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA FFAR1 CTRPv2 pan-cancer AAC 0.15 7e-05
mRNA RHOH CTRPv2 pan-cancer AAC 0.18 7e-05
mRNA RFESD CTRPv2 pan-cancer AAC -0.15 7e-05
mRNA LAMA1 GDSC1000 pan-cancer AAC -0.13 7e-05
mRNA RBM7 CTRPv2 pan-cancer AAC -0.15 7e-05
mRNA CTD-2370N5.3 CTRPv2 pan-cancer AAC 0.18 7e-05
mRNA FHL2 GDSC1000 pan-cancer AAC -0.16 7e-05
mRNA VPS4B CTRPv2 pan-cancer AAC 0.14 7e-05
mRNA HBQ1 CTRPv2 pan-cancer AAC -0.15 7e-05
mRNA KAT6B GDSC1000 pan-cancer AAC 0.13 8e-05
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