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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA NREP CTRPv2 pan-cancer AAC 0.11 0.008
mRNA EPG5 GDSC1000 pan-cancer AAC -0.085 0.008
mRNA FAM167B GDSC1000 pan-cancer AAC -0.095 0.008
mRNA PIK3AP1 CTRPv2 pan-cancer AAC 0.11 0.008
mRNA ZNF596 GDSC1000 pan-cancer AAC 0.084 0.008
mRNA WNK2 CTRPv2 pan-cancer AAC 0.1 0.008
mRNA BECN1 GDSC1000 pan-cancer AAC -0.085 0.008
mRNA SAFB2 GDSC1000 pan-cancer AAC 0.087 0.008
mRNA AGTR1 GDSC1000 pan-cancer AAC -0.084 0.008
mRNA OTOA CTRPv2 pan-cancer AAC 0.096 0.008
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