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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA F12 GDSC1000 pan-cancer AAC -0.091 0.008
mRNA FRRS1 GDSC1000 pan-cancer AAC -0.082 0.008
mRNA TFAP2D GDSC1000 pan-cancer AAC -0.079 0.008
mRNA KCNK13 GDSC1000 pan-cancer AAC -0.08 0.008
mRNA EIF2B2 CTRPv2 pan-cancer AAC -0.1 0.008
mRNA NEDD4L GDSC1000 pan-cancer AAC -0.09 0.008
mRNA RP11-249C24.12 CTRPv2 pan-cancer AAC 0.096 0.008
mRNA PANK1 GDSC1000 pan-cancer AAC 0.086 0.008
mRNA CASP4 CTRPv2 pan-cancer AAC -0.1 0.008
mRNA ST6GALNAC1 CTRPv2 pan-cancer AAC -0.099 0.008
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