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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA HNRNPH3 GDSC1000 pan-cancer AAC 0.088 0.008
mRNA PIK3IP1 CTRPv2 pan-cancer AAC 0.1 0.008
mRNA VPS13B GDSC1000 pan-cancer AAC 0.09 0.008
mRNA PRKRIP1 CTRPv2 pan-cancer AAC 0.11 0.008
mRNA SLC35D2 GDSC1000 pan-cancer AAC -0.11 0.008
mRNA RSRC2 GDSC1000 pan-cancer AAC 0.087 0.008
mRNA SMARCA4 GDSC1000 pan-cancer AAC 0.086 0.008
mRNA ZHX1-C8orf76 CTRPv2 pan-cancer AAC 0.1 0.008
mRNA RASSF8 GDSC1000 pan-cancer AAC -0.091 0.008
mRNA IRS2 CTRPv2 pan-cancer AAC -0.11 0.008
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