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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA FRG1 GDSC1000 pan-cancer AAC 0.093 0.007
mRNA BEND3 GDSC1000 pan-cancer AAC 0.089 0.007
mRNA CLVS1 GDSC1000 pan-cancer AAC -0.09 0.007
mRNA LY9 CTRPv2 pan-cancer AAC 0.11 0.007
mRNA AQP10 CTRPv2 pan-cancer AAC -0.098 0.007
mRNA TSPAN33 CTRPv2 pan-cancer AAC 0.1 0.007
mRNA EHMT2 GDSC1000 pan-cancer AAC 0.086 0.007
mRNA IGSF8 GDSC1000 pan-cancer AAC -0.094 0.007
mRNA DNASE1 CTRPv2 pan-cancer AAC 0.1 0.007
mRNA PAXBP1 GDSC1000 pan-cancer AAC 0.095 0.007
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