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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA RGS13 GDSC1000 pan-cancer AAC 0.089 0.006
mRNA KBTBD3 GDSC1000 pan-cancer AAC 0.084 0.006
mRNA CHST11 CTRPv2 pan-cancer AAC -0.11 0.006
mRNA PRDM15 GDSC1000 pan-cancer AAC 0.09 0.006
mRNA NPHS1 GDSC1000 pan-cancer AAC -0.082 0.006
mRNA AFTPH CTRPv2 pan-cancer AAC 0.11 0.006
mRNA TMEM38A CTRPv2 pan-cancer AAC 0.1 0.006
mRNA CCBE1 GDSC1000 pan-cancer AAC -0.09 0.006
mRNA PRSS38 CTRPv2 pan-cancer AAC 0.099 0.006
mRNA CBR1 GDSC1000 pan-cancer AAC -0.096 0.006
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