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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA MIA3 GDSC1000 pan-cancer AAC 0.086 0.006
mRNA NPC1 GDSC1000 pan-cancer AAC -0.091 0.006
mRNA TET3 GDSC1000 pan-cancer AAC 0.094 0.006
mRNA CSF2RB CTRPv2 pan-cancer AAC -0.11 0.006
mRNA RASAL1 CTRPv2 pan-cancer AAC 0.1 0.006
mRNA CYP39A1 CTRPv2 pan-cancer AAC 0.1 0.006
mRNA DUSP21 CTRPv2 pan-cancer AAC -0.099 0.006
mRNA FAM69A GDSC1000 pan-cancer AAC -0.089 0.006
mRNA TOR3A CTRPv2 pan-cancer AAC 0.11 0.006
mRNA FCRLA CTRPv2 pan-cancer AAC 0.11 0.006
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