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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA ELF1 GDSC1000 pan-cancer AAC 0.12 0.005
mRNA DTX1 GDSC1000 pan-cancer AAC 0.097 0.005
mRNA ZNF76 GDSC1000 pan-cancer AAC 0.09 0.005
mRNA ATP1B2 GDSC1000 pan-cancer AAC 0.084 0.005
mRNA SLA2 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA B4GALT5 GDSC1000 pan-cancer AAC -0.091 0.005
mRNA RCOR2 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA SPATS2L GDSC1000 pan-cancer AAC -0.11 0.005
mRNA WT1 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA GNG7 CTRPv2 pan-cancer AAC 0.11 0.005
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