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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA PLEK2 CTRPv2 pan-cancer AAC -0.13 0.005
mRNA UBASH3B CTRPv2 pan-cancer AAC -0.1 0.005
mRNA MEPCE GDSC1000 pan-cancer AAC 0.086 0.005
mRNA WASL GDSC1000 pan-cancer AAC -0.13 0.005
mRNA HGS CTRPv2 pan-cancer AAC -0.11 0.005
mRNA CTHRC1 GDSC1000 pan-cancer AAC -0.091 0.005
mRNA PIKFYVE GDSC1000 pan-cancer AAC 0.11 0.005
mRNA RAB31 GDSC1000 pan-cancer AAC -0.099 0.005
mRNA LELP1 GDSC1000 pan-cancer AAC 0.086 0.005
mRNA WSCD2 CTRPv2 pan-cancer AAC -0.1 0.005
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