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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA BDNF GDSC1000 pan-cancer AAC -0.096 0.005
mRNA PANX2 CTRPv2 pan-cancer AAC -0.11 0.005
mRNA CD79A CTRPv2 pan-cancer AAC 0.11 0.005
mRNA SDC4 GDSC1000 pan-cancer AAC -0.12 0.005
mRNA ZNF630 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA TP53TG3B CTRPv2 pan-cancer AAC -0.11 0.005
mRNA ADIPOR1 GDSC1000 pan-cancer AAC -0.091 0.005
mRNA CHD3 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA MANF GDSC1000 pan-cancer AAC -0.086 0.005
mRNA RAB7A GDSC1000 pan-cancer AAC -0.094 0.005
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